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Cure of HIV: No More A Dream

Submitted by on March 21, 2013 – 11:52 PM 2 Comments

_58438021_m0501034-hiv_particles,_comHIV is one of the most common causes of infectious disease mortality despite advancements in its management in the previous decades. Despite the central role of highly active anti-retroviral therapy, the disease was traditionally considered “incurable” and hence the management relied on life long administration of drugs, typically combination of nucleoside reverse transcriptase inhibitors in combination with protease inhibitors. The life long administration besides being financially cumbersome, poses compliance issues and the high prevalence of adverse effects increases morbidity of patients.

 

The recent past has witnessed several cases of successful eradication of the virus from several patients, atleast to the level of “functional cure”, defined as non-detection of viremia in the absence of anti-retroviral treatment. As students of medicine, we were taught that the CCR5 mutation confers resistance to HIV infection, courtesy of difficulty of the virus in entering the human cell. At that time I had no clue that this mutation will be utilized in the clinical management of disease.

 

In february 2009, New England Journal of Medicine published a case report of an HIV positive adult with leukemia, who received stem cell transplantation from a donor with deletion in the CCR5. Surprisingly, the patient was cured for both leukemia and HIV and showed undetectable viremia even at 20 months of follow up. At that time, it was hypothesized that immune reconstitution might lead to resurgence of the infection which might be latent. However, a relapse has not been seen to date and the patient is popularly termed as “Berlin” patient (Berlin specifies the city of Germany to which the patient belongs).

 

Much more recently, in earlier March 2013, the successful care of an infant with HIV gained widespread media coverage. This infant who was HIV positive due to vertical transmission was treated with a full 3 drug regimen (Zidovudine, lamivudine and Nevirapine) in contrast with the one drug regimen (Zidovudine) used for such patient population. Unfortunately, the mother was lost to follow up. However, after 18 months, the child was relocated and to much surprise was found to be having undetectable viremia which in the absence of treatment suggests functional care.

 

These cases have risen hopes of the hundreds of thousands of HIV patients across the globe and it is a distinct possibility that a widespread cure might be available in the future.

 

 

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  • Susan Moore

    Dr Okoh God will continue to bless you more abundantly, for the good works you are doing in peoples life, I will keep on writing good and posting testimonies about you on the Internet, I’m Susan moore from San Juan, Puerto Rico. I was tested HIV positive, I saw a blog on how Dr Okoh cured people, i did not believe but i just decided to give him a try, I contacted him and also got my healing, i am so happy. If you have any problem or you are also infected with any disease, kindly contact him now with his Email: dr.okohspellhome@gmail.com or call him on +2348110745051 ,

  • Smith Morgan

    am greatful to a great doctor called ramah,he saved me from death,i was hiv positive for over 4years,and i have spend alot of money on it,have being on HIV treatment for years and i still have the virus in me,i almost gave up on death,untill i find a friend of mine who told me about a particular spell caster and an harbalist who helped her sister husband to cure his HIV,at first i thought she was joking,i later gave it a try,and i contacted the doctor on his email,and he replied me immediately and told me what to do,wish i did,days after a pacel was deliver to me containing liquid drugs,wish i took for 18days and he called me to send my full details of myself,that he is going to cast a spell out of me,wish i did,days after, i went to the hospital and i was confirm negative,i was shocked and could not even believed it,till i was confirm negative in another hospital,doctor may the good lord bless you and grant you long life,so you can help those who need your help,u can contact doctor ramah via email Dr.ramahherbalhome@gmail.com or call him via +2348066159471